[Regulation of promoter activity through electrostatic interactions with RNA-polymerase].
Biofizika
; 52(2): 228-36, 2007.
Article
en Ru
| MEDLINE
| ID: mdl-17477049
Electrostatic profiles for sigma70-specific promoters of T4 bacteriophage and four consensus-like synthetic promoters have been calculated. It was shown that the promoters can be classified according to the presence of some specific electrostatic elements located in the far upstream region of their DNAs. A correlation between the electrostatic elements specific for promoters and their functional behaviour was established. A general scheme of promotor activity regulation through electrostatic interactions between the upstream region of promoter DNA and the RNA-polymerase a-subunit was suggested.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ARN Polimerasas Dirigidas por ADN
/
Regulación Viral de la Expresión Génica
/
Regiones Promotoras Genéticas
/
Bacteriófago T4
Idioma:
Ru
Revista:
Biofizika
Año:
2007
Tipo del documento:
Article
Pais de publicación:
Rusia