Label-free detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer.
Acta Trop
; 102(1): 63-8, 2007 Apr.
Article
en En
| MEDLINE
| ID: mdl-17451631
Impedance spectroscopy is a powerful tool for label-free analysis and characterisation of living cells. In this work, we achieved the detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer. The cellular modifications caused by the intracellular parasite result in a shift in impedance which can be measured dielectrically. Thus, a rapid cell-by-cell detection with microliter amounts of reagents is possible. Unlike other diagnostic tests, this method does not depend on extensive sample pre-treatment or expensive chemicals and equipment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Análisis Espectral
/
Babesiosis
/
Enfermedades de los Bovinos
/
Babesia bovis
/
Eritrocitos
/
Citometría de Flujo
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
Límite:
Animals
Idioma:
En
Revista:
Acta Trop
Año:
2007
Tipo del documento:
Article
País de afiliación:
Suiza
Pais de publicación:
Países Bajos