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Association between fluconazole susceptibility and genetic relatedness among Candida tropicalis isolates in Taiwan.
Wang, Jang-Shiun; Li, Shu-Ying; Yang, Yun-Liang; Chou, Hsiao-Hui; Lo, Hsiu-Jung.
Afiliación
  • Wang JS; Division of Clinical Research, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, Republic of China.
  • Li SY; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China.
  • Yang YL; Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, Republic of China.
  • Chou HH; Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, Republic of China.
  • Lo HJ; Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, Republic of China.
J Med Microbiol ; 56(Pt 5): 650-653, 2007 May.
Article en En | MEDLINE | ID: mdl-17446288
Among the 162 Candida tropicalis isolates collected in the Taiwan Surveillance of Antimicrobial Resistance of Yeasts in 1999, 23 (14.2 %) had fluconazole MICs > or = 64 mg l(-1), and thus fulfilled the definition of resistance. Random amplified polymorphic DNA assay showed that all 23 fluconazole-resistance C. tropicalis isolates collected from different hospitals around Taiwan were closely related. Two distinct pulsotypes associated with fluconazole susceptibility were identified when these 23 resistant isolates, along with 13 susceptible ones, were analysed by PFGE.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Candidiasis / Fluconazol / Farmacorresistencia Fúngica / Candida tropicalis Tipo de estudio: Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Med Microbiol Año: 2007 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Candidiasis / Fluconazol / Farmacorresistencia Fúngica / Candida tropicalis Tipo de estudio: Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Med Microbiol Año: 2007 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido