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Meta-analysis of short-term and long-term outcomes of J, W and S ileal reservoirs for restorative proctocolectomy.
Lovegrove, R E; Heriot, A G; Constantinides, V; Tilney, H S; Darzi, A W; Fazio, V W; Nicholls, R J; Tekkis, P P.
Afiliación
  • Lovegrove RE; Imperial College London, Department of Biosurgery and Surgical Technology, St Mary's Hospital, London, UK.
Colorectal Dis ; 9(4): 310-20, 2007 May.
Article en En | MEDLINE | ID: mdl-17432982
OBJECTIVE: The choice of ileal pouch reservoir has been a contentious subject with no consensus as to which technique provides better function. This study aimed to compare short- and long-term outcomes of three ileal reservoir designs. METHOD: Comparative studies published between 1985 and 2000 of J, W and S ileal pouch reservoirs were included. Meta-analytical techniques were employed to compare postoperative complications, pouch failure, and functional and physiological outcomes. Quality of life following surgery was also assessed. RESULTS: Eighteen studies, comprising 1519 patients (689 J pouch, 306 W pouch and 524 S pouch) were included. There was no significant difference in the incidence of early postoperative complications between the three groups. The frequency of defecation over 24 h favoured the use of either a W or S pouch [J vs S: weighted mean difference (WMD) 1.48, P < 0.001; J vs W: WMD 0.97, P = 0.01]. The S pouch was associated with an increased need for pouch intubation (S vs J: OR 6.19, P = 0.04). The use of a J pouch was associated with a significantly higher prevalence of use of anti-diarrhoeal medication (J vs S: OR 2.80, P = 0.01; J vs W: OR 3.55, P < 0.001). CONCLUSION: All three reservoirs had similar perioperative complication rates. The S pouch was associated with the need for anal intubation. There was less frequency and less need for antidiarrhoeal agents with the W rather than the J pouch.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proctocolectomía Restauradora / Evaluación de Resultado en la Atención de Salud / Reservorios Cólicos Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Aspecto: Equity_inequality / Patient_preference Límite: Humans Idioma: En Revista: Colorectal Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2007 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proctocolectomía Restauradora / Evaluación de Resultado en la Atención de Salud / Reservorios Cólicos Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Aspecto: Equity_inequality / Patient_preference Límite: Humans Idioma: En Revista: Colorectal Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2007 Tipo del documento: Article Pais de publicación: Reino Unido