Chronic vasculitis and polyneuropathy due to infection with Bartonella henselae.
Infection
; 35(2): 107-9, 2007 Apr.
Article
en En
| MEDLINE
| ID: mdl-17401716
Bartonella henselae, the causative agent of cat scratch disease and bacillary angiomatosis, is associated with an expanding spectrum of diseases. Here, we report on a 40-year-old patient suffering from chronic recurrent painful ulcers of the toes, distal axonal sensomotor polyneuropathy and Raynaud's phenomenon. Biopsy of the sural nerve demonstrated an axonal neuropathy with a neurogenic muscular atrophy. Treatment with high dose corticosteroids had no beneficial effect. A biopsy taken from a recurring ulcer 7 years after the beginning of the disease revealed superficial ulcerated hyperkeratosis with subepithelial proliferation of small vessels compatible with a diagnosis of verruca peruana, however, without detection of microorganism. Serologic analysis revealed an elevated IFT titer of 1:1,024 against B. henselae. Treatment with erythromycin induced healing of the ulcer, remission of the vasculitis and the polyneuropathy, and a decline of the IFT titer. This case illustrates that B. henselae infection should be considered in patients with vasculitis and polyneuropathic syndromes.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polineuropatías
/
Vasculitis
/
Angiomatosis Bacilar
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Infection
Año:
2007
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
Alemania