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Demonstration of "owl's eye" morphology by confocal microscopy in a patient with presumed cytomegalovirus corneal endotheliitis.
Shiraishi, Atsushi; Hara, Yuko; Takahashi, Miyabi; Oka, Naoko; Yamaguchi, Masahiko; Suzuki, Takashi; Uno, Toshihiko; Ohashi, Yuichi.
Afiliación
  • Shiraishi A; Department of Ophthalmology, Ehime University School of Medicine, Shitsukawa, Toon, Ehime, Japan. shiraia@m.ehime-u.ac.jp <shiraia@m.ehime-u.ac.jp>
Am J Ophthalmol ; 143(4): 715-7, 2007 Apr.
Article en En | MEDLINE | ID: mdl-17386293
PURPOSE: To report confocal microscopic observations of characteristic corneal endothelial lesions in a patient with presumed cytomegalovirus (CMV) corneal endotheliitis. DESIGN: Case report. METHODS: A 77-year-old, immunocompetent man was admitted with corneal edema, keratic precipitates, and coin-shaped lesions in the right eye. Confocal microscopy was performed to examine the corneal endothelium. Polymerase chain reaction (PCR) was used to identify viral DNA in an aqueous humor sample. RESULTS: CMV DNA was detected by PCR. Confocal microscopy showed large corneal endothelial cells with an area of high reflection in the nucleus surrounded by a halo of low reflection. This "owl's eye" morphology is characteristic of CMV infection. Topical and intravenous ganciclovir treatment resulted in rapid resolution of the corneal precipitates and edema, followed by disappearance of the owl's eye morphology. CONCLUSIONS: Confocal microscopy can detect the owl's eye morphology in the corneal endothelium of patients with presumed CMV corneal endotheliitis.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotelio Corneal / Infecciones Virales del Ojo / Infecciones por Citomegalovirus / Microscopía Confocal / Queratitis Tipo de estudio: Prognostic_studies Límite: Aged / Humans / Male Idioma: En Revista: Am J Ophthalmol Año: 2007 Tipo del documento: Article Pais de publicación: Estados Unidos
Buscar en Google
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Imprimir
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotelio Corneal / Infecciones Virales del Ojo / Infecciones por Citomegalovirus / Microscopía Confocal / Queratitis Tipo de estudio: Prognostic_studies Límite: Aged / Humans / Male Idioma: En Revista: Am J Ophthalmol Año: 2007 Tipo del documento: Article Pais de publicación: Estados Unidos