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Knowledge of and attitudes about Alzheimer disease genetics: report of a pilot survey and two focus groups.
Moscarillo, T J; Holt, H; Perman, M; Goldberg, S; Cortellini, L; Stoler, J M; DeJong, W; Miles, B J; Albert, M S; Go, R C P; Blacker, D.
Afiliación
  • Moscarillo TJ; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA.
Community Genet ; 10(2): 97-102, 2007.
Article en En | MEDLINE | ID: mdl-17380059
OBJECTIVES: In preparation for the development of an educational intervention on Alzheimer disease (AD) genetics, we undertook a pilot survey of knowledge in this area and attitudes toward genetic testing for AD among individuals with a family history of AD. METHODS: For the pilot study, we administered a 30-min questionnaire to 57 unaffected individuals from a genetic linkage study. For the focus groups, we interviewed two groups of subjects, ages 44-70 years, with a family history of AD, one of 10 Caucasians and the other of 6 African-Americans. RESULTS: The pilot study showed that there was limited knowledge of genetics overall and AD genetics in particular, considerable concern about personal risk, and little knowledge of or interest in genetic testing for the disease. The focus groups reinforced and fleshed out these impressions and highlighted the importance of caregiving experience in the attitudes toward personal risk for AD. CONCLUSIONS: These results underscore the value of genetics education for this and other complex diseases and suggest specific foci for educational interventions.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas Genéticas / Conocimientos, Actitudes y Práctica en Salud / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Community Genet Asunto de la revista: GENETICA MEDICA Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas Genéticas / Conocimientos, Actitudes y Práctica en Salud / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Community Genet Asunto de la revista: GENETICA MEDICA Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza