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Congenital lung malformations in the second trimester: prenatal ultrasound diagnosis and pathologic findings.
Harmath, Agnes; Csaba, Akos; Hauzman, Erik; Hajdú, Júlia; Pete, Barbara; Papp, Zoltán.
Afiliación
  • Harmath A; Department of Obstetrics and Gynecology, Semmelweis University Faculty of Medicine, H-1088 Budapest, Baross u. 27, Hungary.
J Clin Ultrasound ; 35(5): 250-5, 2007 Jun.
Article en En | MEDLINE | ID: mdl-17373682
PURPOSE: To correlate prenatal sonographic diagnosis of cystic lung malformations with fetopathologic findings after termination of pregnancy. METHODS: We retrospectively analyzed the data of 16 terminated cases in which a cystic lung lesion was diagnosed pre- or postnatally. RESULTS: On average, prenatal diagnosis was established on the 21(st) gestational week (range, 19-26 weeks). The cause of termination was severe polyhydramnios in 4 cases, nonimmune fetal hydrops in 4 cases, other congenital malformation in 5 cases (renal malformation, 2 cases; congenital diaphragmatic hernia, 3 cases), and obstetrical conditions (intrauterine death, placental abruption, spontaneous abortion) in 3 cases. In 11 cases, congenital cystic adenomatoid malformation (CCAM) was the presumptive prenatal diagnosis. Autopsy confirmed the prenatal diagnosis in 6 of them, while in the other 5 cases, an enteric cyst, a laryngeal atresia, an unidentified tumor, a pulmonary hypoplasia, and an extralobar pulmonary sequestration were found on histologic examination. On the other hand, the autopsy revealed CCAM in those 5 cases in which other malformations were suggested prenatally. CONCLUSION: The prenatal sonographic diagnosis of CCAM is difficult. Our cases emphasize the important role of fetopathology even today in the verification of prenatal diagnosis based on sonographic examinations.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malformación Adenomatoide Quística Congénita del Pulmón / Ultrasonografía Prenatal / Pulmón Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Clin Ultrasound Año: 2007 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malformación Adenomatoide Quística Congénita del Pulmón / Ultrasonografía Prenatal / Pulmón Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Clin Ultrasound Año: 2007 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos