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The investigation of Chlamydophila pneumoniae in patients with multiple sclerosis.
Budak, Fatma; Keçeli, Sema; Efendi, Hüsnü; Budak, Faik; Vahaboglu, Haluk.
Afiliación
  • Budak F; Kocaeli University, Medical School, Department of Medical Microbiology, Kocaeli, Turkey. budak@isbank.net.tr
Int J Neurosci ; 117(3): 409-15, 2007 Mar.
Article en En | MEDLINE | ID: mdl-17365124
Totally 32 cerebrospinal fluid samples from Multiple sclerosis (MS) patients were collected. DNA was extracted by High Pure PCR Template Preparation Kit. Two genomic segments, outer membrane protein genes ompA and omp9, were targeted for the detection of C. pneumoniae DNA in the samples by PCR tests. To detect ompA, a nested-PCR assay was designed, whereas for omp9, a PCR-Enyzme immunoassay (PCR-EIA) depending on streptavidin-biotin capture and dig detection of the PCR products was performed. C. pneumoniae DNA was not detected by each assays in patient samples.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Chlamydophila pneumoniae / Infecciones por Chlamydophila / Esclerosis Múltiple Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Neurosci Año: 2007 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Chlamydophila pneumoniae / Infecciones por Chlamydophila / Esclerosis Múltiple Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Neurosci Año: 2007 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido