Your browser doesn't support javascript.
loading
Relevance of serum IgE estimation in allergic bronchial asthma with special reference to food allergy.
Kumar, Raj; Singh, Bhanu P; Srivastava, Prakriti; Sridhara, Susheela; Arora, Naveen; Gaur, Shailendra N.
Afiliación
  • Kumar R; Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, India. rajkumar_27563@yahoo.co.in
Asian Pac J Allergy Immunol ; 24(4): 191-9, 2006 Dec.
Article en En | MEDLINE | ID: mdl-17348241
Studies suggest the importance of serum total and specific IgE in clinical evaluation of allergic manifestations. Such studies are lacking in Indian subcontinent, though a large population suffer from bronchial asthma. Here relevance of serum total and specific IgE was investigated in asthmatics with food sensitization. A total of 216 consecutive patients (mean age 31.9 years, S.D. 11.8) were screened by various diagnostic testing. Out of 216 patients, 172 were with elevated serum total IgE (201 to > 800 IU/ml). Rice elicited marked positive skin prick test reactions (SPT) in 24 (11%) asthma patients followed by black gram 22 (10%), lentil 21 (9.7%) and citrus fruits 20 (9.2%). Serum total IgE and specific IgE showed significant correlation, p = 0.005 and p = 0.001, respectively, with positive skin tests. Blinded food challenges (DBPCFC) with rice and or black gram confirmed food sensitization in 28-37% of cases. In summary, serum total IgE of 265 IU/ml or more with marked positive SPT (4 mm or more) can serve as marker for atopy and food sensitization. Specific IgE, three times of normal controls correlates well with positive DBPCFC and offers evidence for the cases of food allergy.
Asunto(s)
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oryza / Inmunoglobulina E / Alérgenos / Hipersensibilidad a los Alimentos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Asian Pac J Allergy Immunol Año: 2006 Tipo del documento: Article País de afiliación: India Pais de publicación: Tailandia
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oryza / Inmunoglobulina E / Alérgenos / Hipersensibilidad a los Alimentos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Asian Pac J Allergy Immunol Año: 2006 Tipo del documento: Article País de afiliación: India Pais de publicación: Tailandia