Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection.

Valcour, V G; Sithinamsuwan, P; Nidhinandana, S; Thitivichianlert, S; Ratto-Kim, S; Apateerapong, W; Shiramizu, B T; Desouza, M S; Chitpatima, S T; Watt, G; Chuenchitra, T; Robertson, K R; Paul, R H; McArthur, J C; Kim, J H; Shikuma, C M

Valcour, V G; Sithinamsuwan, P; Nidhinandana, S; Thitivichianlert, S; Ratto-Kim, S; Apateerapong, W; Shiramizu, B T; Desouza, M S; Chitpatima, S T; Watt, G; Chuenchitra, T; Robertson, K R; Paul, R H; McArthur, J C; Kim, J H; Shikuma, C M.

Afiliación

Valcour VG; Hawaii AIDS Clinical Research Program, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA. Vvalcour@hawaii.edu

Neurology ; 68(7): 525-7, 2007 Feb 13.

Article en En | MEDLINE | ID: mdl-17296919

RESUMEN

HIV-associated dementia (HAD) is not firmly established in patients with circulating recombinant form (CRF) 01_AE HIV-1. In this study, we compared neuropsychological performance among 15 Thai individuals with HAD, 15 Thai individuals without HAD, and 30 HIV-negative control subjects. HIV-1 participants were highly active anti-retroviral therapy naive and matched by age, education, and CD4 count. Neuropsychological testing abnormalities were identified in most cognitive domains among HAD vs HIV-negative participants, confirming the presence of HAD in CRF01_AE.

Asunto(s)

Complejo SIDA Demencia/virología; VIH-1/clasificación; VIH-1/genética; Trastornos Mentales/virología; Enfermedades del Sistema Nervioso/virología; Recombinación Genética; Complejo SIDA Demencia/sangre; Complejo SIDA Demencia/psicología; Adulto; Cognición; Estudios de Cohortes; Femenino; Humanos; Masculino; Pruebas Neuropsicológicas; Índice de Severidad de la Enfermedad

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recombinación Genética / Complejo SIDA Demencia / VIH-1 / Trastornos Mentales / Enfermedades del Sistema Nervioso Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Neurology Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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