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In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis.
Hongmanee, Poonpilas; Rukseree, Kamolchanok; Buabut, Benjamas; Somsri, Boontiwa; Palittapongarnpim, Prasit.
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  • Hongmanee P; Division of Microbiology, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Road, Bangkok 10400, Thailand. Poonpilas@hotmail.com
Antimicrob Agents Chemother ; 51(3): 1105-6, 2007 Mar.
Article en En | MEDLINE | ID: mdl-17178795
The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 microg/ml. The MIC(50) and MIC(90) were 0.125 and 0.25 microg/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cloroquinolinoles / Mycobacterium tuberculosis / Antituberculosos Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2007 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Estados Unidos
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cloroquinolinoles / Mycobacterium tuberculosis / Antituberculosos Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2007 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Estados Unidos