Rhabdomyoblastic differentiation in malignant melanoma in adults: report of 2 cases.

Gharpuray-Pandit, Deepa; Coyne, John; Eyden, Brian; Banerjee, S Sankar

Gharpuray-Pandit, Deepa; Coyne, John; Eyden, Brian; Banerjee, S Sankar.

Afiliación

Gharpuray-Pandit D; Department of Histopathology, Christie Hospital NHS Trust, Manchester, United Kingdom.

Int J Surg Pathol ; 15(1): 20-5, 2007 Jan.

Article en En | MEDLINE | ID: mdl-17172493

RESUMEN

Two cases of malignant melanoma are reported in adults exhibiting rhabdomyoblastic differentiation to alert pathologists to this rare variant of malignant melanoma. One of the cases presented as a metastasis in a submandibular lymph node, and the other was a primary skin melanoma. There are only a few published reports on melanocytic tumors with rhabdomyoblastic differentiation, mainly occurring in giant congenital nevi. Both cases reported here were confirmed by immunohistochemistry. Both cases were also studied by electron microscopy, and one showed distinctive ultrastructural features of striated muscle.

Asunto(s)

Melanoma/patología; Neoplasias Cutáneas/patología; Adulto; Anciano de 80 o más Años; Femenino; Humanos; Inmunohistoquímica; Masculino; Melanoma/metabolismo; Microscopía Electrónica de Transmisión; Neoplasias Cutáneas/metabolismo

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Melanoma Límite: Adult / Aged80 / Female / Humans / Male Idioma: En Revista: Int J Surg Pathol Asunto de la revista: PATOLOGIA Año: 2007 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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