The recent evolution of pentachlorophenol (PCP)-4-monooxygenase (PcpB) and associated pathways for bacterial degradation of PCP.
Biodegradation
; 18(5): 525-39, 2007 Oct.
Article
en En
| MEDLINE
| ID: mdl-17123025
Man-made polychlorinated phenols such as pentachlorophenol (PCP) have been used extensively since the 1920s as preservatives to prevent fungal attack on wood. During this time, they have become serious environmental contaminants. Despite the recent introduction of PCP in the environment on an evolutionary time scale, PCP-degrading bacteria are present in soils worldwide. The initial enzyme in the PCP catabolic pathway of numerous sphingomonads, PCP-4-monooxygenase (PcpB), catalyzes the para-hydroxylation of PCP to tetrachlorohydroquinone and is encoded by the pcpB gene. This review examines the literature concerning pcpB and supports the suggestion that pcpB/PcpB should be considered a model system for the study of recent evolution of catabolic pathways among bacteria that degrade xenobiotic molecules introduced into the environment during the recent past.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pentaclorofenol
/
Biodegradación Ambiental
/
Oxigenasas de Función Mixta
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Revista:
Biodegradation
Asunto de la revista:
BIOQUIMICA
/
SAUDE AMBIENTAL
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Países Bajos