Plasma level of mitochondrial coupling factor 6 increases in patients with type 2 diabetes mellitus.
Int J Cardiol
; 117(3): 411-2, 2007 May 02.
Article
en En
| MEDLINE
| ID: mdl-16899312
Coupling factor 6 (CF6) is a novel endogenous inhibitor of prostacyclin. Plasma CF6 and 6-keto-PGF(1a) were measured by radioimmunoassay in 70 consecutively recruited patients with type 2 diabetes and in 56 healthy controls. A significantly increased plasma CF6 level was found in diabetics compared with controls. The CF6 level was inversely correlated with plasma 6-keto-PGF(1a) level and positively correlated with blood glucose and lipids. These results suggest that CF6 might be an obvious marker of impaired endothelium and might contribute to vascular damage in diabetes.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factores de Acoplamiento de la Fosforilación Oxidativa
/
ATPasas de Translocación de Protón Mitocondriales
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Diabetes Mellitus Tipo 2
Límite:
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Cardiol
Año:
2007
Tipo del documento:
Article
Pais de publicación:
Países Bajos