[Structural-functional organization of Golgi apparatus].
Tsitologiia
; 48(4): 283-307, 2006.
Article
en Ru
| MEDLINE
| ID: mdl-16841491
This review is dedicated to the structure and function of Golgi apparatus (GA). It summarizes contemporary data published in numerous experimental papers and in several reviews. Possible ways of intra-Golgi transport of proteins, existent models of structural and functional organization of Golgi organelle, as well as the issues of its biogenesis, posttranslational modification and sorting of proteins and lipids, and mechanisms of their traffic-king are discussed. Special attention is paid to the role of coatomer proteins (COPI, COPII and clathrin), fusion proteins (SNAREs), and small GTPases (ARF, SARI) in the secretory pathway. In addition, the phenomena of ultrastructural alterations of GA due to various functional conditions and physiological stimuli are specifically accented. We included in this review our original data on a probable involvement of GA in water transport, and on the organization of atypical GA in microsporidia--intracellular parasitic protists.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aparato de Golgi
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
Ru
Revista:
Tsitologiia
Año:
2006
Tipo del documento:
Article
Pais de publicación:
Rusia