Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.
Neurology
; 67(1): 146-9, 2006 Jul 11.
Article
en En
| MEDLINE
| ID: mdl-16832096
A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-associated protein TIA-1 and the membranolytic protein granzyme-B. Although recovery was thought to be unlikely, treatment of the PNE with corticosteroids and resection of the associated lung cancer resulted in dramatic improvement for 21 months.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encefalitis
/
Antígenos de Neoplasias
/
Proteínas del Tejido Nervioso
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Neurology
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos