Combined clotrimazole irrigation and depot therapy for canine nasal aspergillosis.
J Small Anim Pract
; 47(6): 312-5, 2006 Jun.
Article
en En
| MEDLINE
| ID: mdl-16761982
OBJECTIVES: To evaluate the effect of short duration 1 per cent clotrimazole flush when combined with 1 per cent clotrimazole cream instilled into the frontal sinuses for the treatment of nasal aspergillosis in 14 dogs. METHODS: Fourteen dogs with clinical, radiological, serological and rhinoscopic findings consistent with nasal aspergillosis were treated by frontal sinus trephination and a short, five-minute flushing of 1 per cent topical clotrimazole solution followed by a 1 per cent clotrimazole cream instilled as a depot agent. RESULTS: Twelve of the 14 dogs (86 per cent) responded well to treatment and either had no clinical signs after treatment or had signs consistent with mild rhinitis during a minimum follow-up period of six months. Only one dog required multiple treatments. Treatment was well tolerated by all patients, with minimal complications. CLINICAL SIGNIFICANCE: This treatment compares favourably to previously published data using one-hour topical clotrimazole or enilconazole flushing treatment protocols. The treatment technique significantly reduced treatment time under anaesthesia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aspergilosis
/
Enfermedades Nasales
/
Clotrimazol
/
Enfermedades de los Perros
/
Antifúngicos
Tipo de estudio:
Guideline
/
Observational_studies
/
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
J Small Anim Pract
Año:
2006
Tipo del documento:
Article
Pais de publicación:
Reino Unido