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A new cytotoxic amide from the stem wood of Hibiscus tiliaceus.
Chen, Jih-Jung; Huang, Shi-Yu; Duh, Chang-Yih; Chen, Ih-Sheng; Wang, Tai-Chi; Fang, Hui-Yu.
Afiliación
  • Chen JJ; Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung, Taiwan, ROC.
Planta Med ; 72(10): 935-8, 2006 Aug.
Article en En | MEDLINE | ID: mdl-16732539
A new coumarin, hibiscusin, and a new amide, hibiscusamide, together with eleven known compounds including vanillic acid, P-hydroxybenzoic acid, syringic acid, P-hydroxybenzaldehyde, scopoletin, N- trans-feruloyltyramine, N-cis-feruloyltyramine, a mixture of beta-sitosterol and stigmasterol, a mixture of beta-sitostenone and stigmasta-4,22-dien-3-one were isolated from the stem wood of Hibiscus tiliaceus. The structures of these new compounds were determined through spectral analyses. Among the isolates, three compounds exhibited cytotoxicity (IC (50) values < 4 microg/mL) against P-388 and/or HT-29 cell lines in vitro.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acrilamidas / Citotoxinas / Hibiscus / Guayacol Idioma: En Revista: Planta Med Año: 2006 Tipo del documento: Article Pais de publicación: Alemania
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acrilamidas / Citotoxinas / Hibiscus / Guayacol Idioma: En Revista: Planta Med Año: 2006 Tipo del documento: Article Pais de publicación: Alemania