[Synthesis of new test reagents for the estrogen receptor in human breast cancer tissues].

Mao, F; Weng, L L; Zheng, H

Mao, F; Weng, L L; Zheng, H.

Afiliación

Mao F; School of Pharmacy, West China University of Medical Sciences, Chengdu.

Yao Xue Xue Bao ; 26(8): 611-4, 1991.

Article en Zh | MEDLINE | ID: mdl-1666730

RESUMEN

According to the character of structure and activity of the test reagents I-IV, two new reagents V and VI for detecting estrogen receptor of human mammary cancer cells were synthesized. This simplifies the route of synthesis and increases activity. Key intermediates VIII and IX were confirmed by IR, MS, UV and elemental analysis. The quantification of the final products V and VI were determined by UV. The result of preliminary clinico-pathological test shows compound V to be effective on estrogen receptor.

Asunto(s)

Neoplasias de la Mama/química; Estradiol/análogos & derivados; Estrógenos Conjugados (USP)/síntesis química; Etinilestradiol/análogos & derivados; Receptores de Estrógenos/análisis; Estradiol/síntesis química; Etinilestradiol/síntesis química; Humanos; Juego de Reactivos para Diagnóstico

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores de Estrógenos / Estrógenos Conjugados (USP) / Estradiol / Etinilestradiol Límite: Humans Idioma: Zh Revista: Yao Xue Xue Bao Año: 1991 Tipo del documento: Article Pais de publicación: China

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