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[Behçet's disease and the possibilities of modern tumour necrosis factor inhibiting medication]. / De ziekte van Behçet en de mogelijkheden van moderne tumornecrosisfactor-remmende medicatie.
van Laar, J A M; Jamnitski, A; Baarsma, G S; van Daele, P L A; van Hagen, P M.
Afiliación
  • van Laar JA; Erasmus MC-Dijkzigt, afd. Inwendige Geneeskunde, sectie Immunologie, afd. Immunologie, Dr.Molewaterplein 40, 3015 GD Rotterdam. j.vanlaar@erasmusmc.nl
Ned Tijdschr Geneeskd ; 150(13): 705-9, 2006 Apr 01.
Article en Nl | MEDLINE | ID: mdl-16623340
A 25-year-old woman was admitted after having had a fever for one month, headache, nausea, vomiting, dysarthria and right-sided hemiparesis. A 35-year-old man was admitted because of severe loss of vision and a history of focal retinochoroiditis. Both were suffering from Behçet's disease. Behçet's disease can present with systemic symptoms that might be related to aberrant T-cell functions. It is treated with a variety of immunoregulatory drugs. Recently, treatment with tumour necrosis factor (TNF) alpha-inhibiting molecular designed drugs such as infliximab or etanercept has improved the therapeutic prospective of Behçet patients. Both of the patients described above developed refractory disease and responded to treatment with these new drugs.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Behçet / Factor de Necrosis Tumoral alfa / Inmunosupresores Límite: Adult / Female / Humans / Male Idioma: Nl Revista: Ned Tijdschr Geneeskd Año: 2006 Tipo del documento: Article Pais de publicación: Países Bajos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Behçet / Factor de Necrosis Tumoral alfa / Inmunosupresores Límite: Adult / Female / Humans / Male Idioma: Nl Revista: Ned Tijdschr Geneeskd Año: 2006 Tipo del documento: Article Pais de publicación: Países Bajos