Neurosensory effects of chronic exposure to arsenic via drinking water in Inner Mongolia: I. Signs, symptoms and pinprick testing.
J Water Health
; 4(1): 29-37, 2006 Mar.
Article
en En
| MEDLINE
| ID: mdl-16604836
This study was designed to assess the effects of exposure to arsenic in drinking water on neurosensory function. A questionnaire including neurological signs and symptoms and a brief neurological exam consisting of pinprick testing of the arms and legs and knee-jerk test were administered to 321 residents of the Bamen region of Inner Mongolia, China. Arsenic in water was measured by hydride generation atomic fluorescence. Participants were divided into three exposure groups--low (non-detectible-20), medium (100-300) and high (400-700 microg/I) arsenic. Significant group differences were observed in pinprick scores for all four limbs. Results indicate that arsenic alters pinprick (pain) thresholds at well-water concentrations as low as 400 microg/l, well below the 1000 microg/l threshold for neurological effect specified by NRC (1999). Regression models suggest that a 50% increase in pinprick score is associated with a 71-159 ppb increase in arsenic concentration.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Arsénico
/
Abastecimiento de Agua
/
Exposición a Riesgos Ambientales
/
Enfermedades del Sistema Nervioso
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Water Health
Asunto de la revista:
SAUDE AMBIENTAL
Año:
2006
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Reino Unido