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Cognitive behaviour therapy and medication in the treatment of obsessive-compulsive disorder.
O'Connor, K P; Aardema, F; Robillard, S; Guay, S; Pélissier, M-C; Todorov, C; Borgeat, F; Leblanc, V; Grenier, S; Doucet, P.
Afiliación
  • O'Connor KP; Fernand-Seguin Research Centre, Louis-H. Lafontaine Hospital, Montreal, QC, Canada. kieron.oconnor@umontreal.ca
Acta Psychiatr Scand ; 113(5): 408-19, 2006 May.
Article en En | MEDLINE | ID: mdl-16603032
OBJECTIVE: To compare cognitive behaviour therapy (CBT) with CBT plus medication; medication alone; and placebo in the treatment of adult obsessive-compulsive disorder (OCD). METHOD: Forty-eight participants (43 completers) were recruited into two protocols. In the first protocol, 21 people with OCD were randomly allocated to either a standard medication (fluvoxamine) or standard placebo condition for a 5-month period. Both these groups subsequently received CBT for a further 5 months. In the second protocol, 22 people with OCD received CBT, one group was already stabilized on an antidepressant of choice; the second group was drug naïve. RESULTS: All active treatments, but not the placebo, showed clinical improvement. There was no difference in treatment response to CBT regardless of whether participants had previously received medication or placebo. CONCLUSION: CBT has a more specific antiobsessional effect than medication but CBT plus medication shows greatest overall clinical improvement in mood.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Cognitivo-Conductual / Antidepresivos / Trastorno Obsesivo Compulsivo Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Acta Psychiatr Scand Año: 2006 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Cognitivo-Conductual / Antidepresivos / Trastorno Obsesivo Compulsivo Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Acta Psychiatr Scand Año: 2006 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos