An optical biosensor for rapid and label-free detection of cells.

Acharya, Ghanashyam; Chang, Chun-Li; Savran, Cagri

Acharya, Ghanashyam; Chang, Chun-Li; Savran, Cagri.

Afiliación

Acharya G; School of Mechanical Engineering, and Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, USA.

J Am Chem Soc ; 128(12): 3862-3, 2006 Mar 29.

Article en En | MEDLINE | ID: mdl-16551065

RESUMEN

We report a broadly applicable optical method for rapid and label-free detection of as few as 45 cells. In this method, bacterial cells are detected by measuring the amount of laser light transmitted through a small glass well functionalized with antibodies which specifically recognize and capture the cells. The described approach is simple, rapid, economical, and promising for portable and high-throughput detection of a wide variety of pathogenic and infectious cells.

Asunto(s)

Técnicas Bacteriológicas/métodos; Técnicas Biosensibles/métodos; Pseudomonas aeruginosa/aislamiento & purificación; Anticuerpos Antibacterianos/química; Especificidad de Anticuerpos; Escherichia coli/inmunología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Técnicas Biosensibles / Técnicas Bacteriológicas Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Am Chem Soc Año: 2006 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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