[A preliminary study of BCG adjuvant therapy in oral and maxillofacial malignant melanoma.].
Shanghai Kou Qiang Yi Xue
; 3(3): 144-5, 1994 Sep.
Article
en Zh
| MEDLINE
| ID: mdl-16538310
Malignant melanoma is a kind of tumor with higher malignant and lower therapeutic effect.it is demonstrated by experiment that melanoma cells have antigenicity and refer to immunology.BCG is a kind of biologic response modifier(BRM).it is able to promote physical antitumor ability.There were 42 patients with oral and maxillofacial malignant melanoma who received freezing therapy and surgery in this paper.11 cases of them added BCG immunotherapy.The result is that the median survival time of therapy plus BCG group is 4 years,and 3 years,5 years,7 years survival rate are 89%,72% and 32%,over 8 years survival rate is 18%.The median survival time of another group is 2 years,and 3 years,5 years,7 years survival rate are 55%,24% and 12%,over 8 years survival rate is 3%.There is a statistically significant difference between these two groups and BCG group has a longer survival time.This preliminary study demonstrated that BCG adjuvant therapy could decrease recurrence of metastases and increase patients survival time.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
Zh
Revista:
Shanghai Kou Qiang Yi Xue
Asunto de la revista:
ODONTOLOGIA
Año:
1994
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
China