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PCV chemotherapy for recurrent glioblastoma.
Schmidt, F; Fischer, J; Herrlinger, U; Dietz, K; Dichgans, J; Weller, M.
Afiliación
  • Schmidt F; Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Medical School, Tuebingen, Germany. friederike.schmidt@uni-tuebingen.de
Neurology ; 66(4): 587-9, 2006 Feb 28.
Article en En | MEDLINE | ID: mdl-16505319
The authors administered procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, lomustine), and vincristine (PCV) to 86 patients with recurrent glioblastoma. There were three partial responses, but no complete responses. Median progression-free survival was 17.1 weeks and progression-free survival at 6 months was 38.4%. World Health Organization grade III/IV hematologic toxicity was common (25.6%), but nonhematologic toxicity was mild.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurology Año: 2006 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurology Año: 2006 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos