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Pulsatile delivery of clarithromycin alone or in combination with amoxicillin against Streptococcus pneumoniae.
Leuthner, Kimberly D; Cheung, Chrissy M; Rybak, Michael J.
Afiliación
  • Leuthner KD; Anti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Antimicrob Agents Chemother ; 50(2): 813-6, 2006 Feb.
Article en En | MEDLINE | ID: mdl-16436754
We evaluated pulsatile dosing of clarithromycin and amoxicillin alone or combined against Streptococcus pneumoniae with various susceptibilities. When combined, pulsatile amoxicillin with clarithromycin was superior to either 8- or 12-h dosing against the intermediate strain and was identical for the susceptible strain. Pulse dosing of antimicrobials warrants further investigation.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Streptococcus pneumoniae / Claritromicina / Amoxicilina / Antibacterianos Idioma: En Revista: Antimicrob Agents Chemother Año: 2006 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Streptococcus pneumoniae / Claritromicina / Amoxicilina / Antibacterianos Idioma: En Revista: Antimicrob Agents Chemother Año: 2006 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos