[Suspicion of metastases in laryngeal carcinomas]. / Predicción de la capacidad metastásica del cáncer de laringe: implicaciones clínicas.
Acta Otorrinolaringol Esp
; 56(10): 477-81, 2005 Dec.
Article
en Es
| MEDLINE
| ID: mdl-16425643
OBJECTIVE: To look for models predicting metastasis in laryngeal/hypopharyngeal carcinomas. DESIGN: Prospective study. PATIENTS: Sixty patients bearing laryngeal squamous cell carcinoma who were treated with curative purposes were followed prospectively with at least 10-year follow-up. PARAMETERS: Clinical (Staging, site, age, alcohol and smoking intake, surgery on the primary tumor, neck surgery) and pathological (size, number of metastatic lymph nodes, T and N staging, degree of differentiation, Jakobsson's and Glanz's scoring of malignancy, both scores in biopsies and surgical specimens) parameters were recorded in each case. METHODS: A multivariate analysis was performed to find out those parameters independently related to presence of metastases. RESULTS: The prospective study rendered tumor burden and Glanz's scoring from biopsies to be independently related with the presence of metastases. CONCLUSIONS: Malignancy grading systems must be included in laryngeal carcinoma patients' planning of neck treatment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
Es
Revista:
Acta Otorrinolaringol Esp
Año:
2005
Tipo del documento:
Article
Pais de publicación:
España