Safety and immunogenicity of a combined DTPa-IPV vaccine administered as a booster from 4 years of age: a review.
Vaccine
; 24(13): 2440-8, 2006 Mar 20.
Article
en En
| MEDLINE
| ID: mdl-16406224
A combined DTPa-IPV booster vaccine was administered as a 4th or 5th dose after DTPa or DTPw priming. Over 99% vaccines developed antibody levels considered to be protective to diphtheria, tetanus and poliovirus, and >95% mounted a response to acellular pertussis antigens. Rectal temperature >39.5 degrees C was observed in at most 3.2% of vaccinees. Swelling >50 mm occurred in 24% of DTPa-primed compared to 5.5% of DTPw-primed children. Large swelling involving the entire upper arm (extending to involve the elbow joint) was reported for up to 1.2% of DTPa-primed subjects, which is consistent with literature reports for other DTPa vaccines.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vacuna Antipolio de Virus Inactivados
/
Vacunas Combinadas
/
Vacunas contra Difteria, Tétanos y Tos Ferina Acelular
Tipo de estudio:
Clinical_trials
Límite:
Child
/
Child, preschool
/
Humans
Idioma:
En
Revista:
Vaccine
Año:
2006
Tipo del documento:
Article
País de afiliación:
Bélgica
Pais de publicación:
Países Bajos