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Emerin increase in regenerating muscle fibers.
Squarzoni, S; Sabatelli, P; Capanni, C; Lattanzi, G; Rutigliano, C; Columbaro, M; Mattioli, E; Rocca, M; Maraldi, N M.
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  • Squarzoni S; ITOI-CNR, Unit of Bologna c/o Istituti Ortopedici Rizzoli, Bologna, Italy. squarzoni@area.bo.cnr.it
Eur J Histochem ; 49(4): 355-62, 2005.
Article en En | MEDLINE | ID: mdl-16377577
The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with respect to normal mature myofibers. This finding suggests an involvement of emerin during the muscle fiber regeneration process, in analogy with its reported involvement in muscle cell differentiation in vitro. The impairment of skeletal muscle physiological regeneration or reorganization could be a possible pathogenetic mechanism for Emery Dreifuss muscular dystrophy.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regeneración / Timopoyetinas / Músculo Esquelético / Fibras Musculares Esqueléticas / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Eur J Histochem Asunto de la revista: HISTOCITOQUIMICA Año: 2005 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
Buscar en Google
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Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regeneración / Timopoyetinas / Músculo Esquelético / Fibras Musculares Esqueléticas / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Eur J Histochem Asunto de la revista: HISTOCITOQUIMICA Año: 2005 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia