High degree of discordance between three-dimensional and two-dimensional lumbar spine bone mineral density in Turner's syndrome.
J Clin Densitom
; 8(4): 461-6, 2005.
Article
en En
| MEDLINE
| ID: mdl-16311432
Low bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) has been described in Turner's syndrome (TS). One of the error factors of DXA is short stature, a common finding in TS patients. Aimed to evaluate the influence of a low stature on BMD, we compared the two-dimensional (2D) or conventional BMD (cBMD) with three-dimensional (3D) or volumetric BMD (vBMD) in 62 females (10 to 48 yr old) with TS diagnosis in a case control study. They were compared to 102 normal females (7 to 45 yr old) grouped by age-ranges. All patients were subjected to a lumbar spine densitometry by DXA in the PA and lateral projections, obtained the cBMD and vBMD and calculated for the apparent BMD (appBMD). In TS, the mean of Z-score for cBMD was significantly lower than that for vBMD and for appBMD (-2.31 +/- 1.42; -0.64 +/- 1.55; and -1.72 +/- 1.5; respectively). Most of the patients (83.8%) had a Z-score <-1 for cBMD, whereas the majority (58.1%) had a Z-score <-1 for vBMD. Concluding, the cBMD underestimates the bone mass of the lumbar spine in patients with TS inducing to false diagnoses of bone fragility. Volumetric BMD approached the bone mass of control patients, while appBMD just partially do that.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Turner
/
Procesamiento de Imagen Asistido por Computador
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Densidad Ósea
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Vértebras Lumbares
Tipo de estudio:
Clinical_trials
/
Etiology_studies
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Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
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Child
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Female
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Humans
/
Middle aged
Idioma:
En
Revista:
J Clin Densitom
Asunto de la revista:
ORTOPEDIA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Estados Unidos