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Morpheaform extra-ocular sebaceous carcinoma.
Innocenzi, D; Balzani, A; Lupi, F; Panetta, C; Skroza, N; Cantoresi, F; Schwartz, R A; Calvieri, S.
Afiliación
  • Innocenzi D; Dermatology and Plastic Surgery, University La Sapienza, Rome, Italy. daniele.innocenzi@uniroma1.it
J Surg Oncol ; 92(4): 344-6, 2005 Dec 15.
Article en En | MEDLINE | ID: mdl-16299801
BACKGROUND: Sebaceous carcinoma is an unusual, aggressive, malignant tumor derived from the epithelium of sebaceous glands. It may arise in ocular or extra-ocular sites and is often evident as an ulcerated or non-ulcerated cystic nodule measuring up to 8 cm in diameter. A significant number of extra-ocular sebaceous carcinomas have been associated with metastases and high mortality rate. METHODS AND RESULTS: We reviewed the literature in the context of our report of a 68-year-old woman who had a morpheaform plaque of the upper lip of 15 years duration, extending into the left naso-genal groove, which histologically also showed marked stromal fibrosis. Three years after excision, there were no signs of recurrence or metastases. CONCLUSIONS: This patient is unusual in clinical and histologic pattern, as a morpheaform appearance has only been described previously in only one sebaceous carcinoma. In addition, no metastatic disease 15 years after tumor onset is a fortunate and remarkable feature.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerodermia Localizada / Neoplasias de las Glándulas Sebáceas / Adenocarcinoma Sebáceo / Labio Límite: Aged / Female / Humans Idioma: En Revista: J Surg Oncol Año: 2005 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerodermia Localizada / Neoplasias de las Glándulas Sebáceas / Adenocarcinoma Sebáceo / Labio Límite: Aged / Female / Humans Idioma: En Revista: J Surg Oncol Año: 2005 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos