[Serum level of soluble forms of membranous antigens of immune system cells in carriers of virus hepatitis G markers].
Vopr Virusol
; 50(5): 19-22, 2005.
Article
en Ru
| MEDLINE
| ID: mdl-16250593
The levels of soluble CD38 (sCD38), CD50 (sCD50), and CD95 (sCD95) antigens and HLA class I (sHLA-I) were determined in the serum samples from persons infected with hepatitis G virus (HGV). HGV monoinfection was accompanied by a rise in the serum content of sCD38, sCD50, and sCD95 antigens. The serum presence of HGV RNA and anti-E2 HGV antibodies was characterized by the normal content of sCD38 and sCD95 while the level of sCD50 was elevated and the serum content of sHLA-I was decreased. If the serum contained only anti-E2 HGV antibodies, the level of sCD50 remained increased 4-fold. It is suggested that the higher adhesion-inhibiting level of sCD50 is a reason of a weak immune response to HGV and hence of a long HGV persistence in the body.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antígenos CD
/
Moléculas de Adhesión Celular
/
Infecciones por Flaviviridae
/
Receptor fas
/
Virus GB-C
/
Hepatitis Viral Humana
/
Antígenos HLA
Idioma:
Ru
Revista:
Vopr Virusol
Año:
2005
Tipo del documento:
Article
Pais de publicación:
Rusia