A genetic and molecular profile of third chromosome centric heterochromatin in Drosophila melanogaster.

Fitzpatrick, K A; Sinclair, D A; Schulze, S R; Syrzycka, M; Honda, B M

Fitzpatrick, K A; Sinclair, D A; Schulze, S R; Syrzycka, M; Honda, B M.

Afiliación

Fitzpatrick KA; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada.

Genome ; 48(4): 571-84, 2005 Aug.

Article en En | MEDLINE | ID: mdl-16094423

RESUMEN

In this review, we combine the results of our published and unpublished work with the published results of other laboratories to provide an updated map of the centromeric heterochromatin of chromosome 3 in Drosophila melanogaster. To date, we can identify more than 20 genes (defined DNA sequences with well-characterized functions and (or) defined genetic complementation groups), including at least 16 essential loci. With the ongoing emergence of data from genetic, cytological, and genome sequencing studies, we anticipate continued, substantial progress towards understanding the function, structure, and evolution of centric heterochromatin.

Asunto(s)

Cromosomas/genética; Drosophila melanogaster/genética; Heterocromatina/genética; Animales; Centrómero/genética; Mapeo Cromosómico; Genes de Insecto/genética

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heterocromatina / Cromosomas / Drosophila melanogaster Límite: Animals Idioma: En Revista: Genome Asunto de la revista: GENETICA Año: 2005 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Canadá

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