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Lower oesophageal sphincter pressure and timed barium oesophagogram: two objective parameters in the non-invasive assessment of primary achalasia.
Montazeri, G; Nouri, N; Estakhri, A; Shirani, S; Derakhshan, M H; Yaghoobi, M; Mikaeli, J; Malekzadeh, R.
Afiliación
  • Montazeri G; Gastroenterology and Hepatology, Digestive Disease Research Center, Tehran University of Medical Science, Shariati Hospital, Tehran, Iran. montazer@ams.ac.ir
Aliment Pharmacol Ther ; 22(3): 261-5, 2005 Aug 01.
Article en En | MEDLINE | ID: mdl-16091064
BACKGROUND: The non-invasive assessment of primary achalasia is not precise. AIM: To compare investigations before and 1 month after balloon dilation in achalasia. METHODS: Fifty-two patients with primary achalasia were enrolled. Subjective and objective variables of oesophageal functions were analysed before and 1 month after balloon dilation. RESULTS: The mean predilation symptom score, lower oesophageal sphincter pressure, height and volume of barium at 5 min were 7.7 +/- 2.6, 62.0 +/- 25.1 mmHg, 9.2 +/- 6.1 cm and 53.2 +/- 49.8 mL respectively; the mean postdilation values were 3.0 +/- 3.0, 34.1 +/- 12.5 mmHg, 7.9 +/- 5.1 cm and 28.0 +/- 30.1 mL respectively. The before dilation volume of barium at 5 min correlates significantly with lower oesophageal sphincter pressure (P < 0.01). The mean symptom scores, lower oesophageal sphincter pressure and volume of barium at 5 min dropped significantly after intervention (P < 0.01), but the reduction in barium height at 5 min was not significant. The percentage changes in volume at 5 min significantly predicted the percentage changes in lower oesophageal sphincter pressure (P < 0.01). CONCLUSIONS: The volume of barium retention at 5 min can predict the lower oesophageal sphincter pressure before and after balloon dilation in primary achalasia. This could be used as a non-invasive objective tool for initial and post-dilation assessment.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acalasia del Esófago / Esfínter Esofágico Inferior Tipo de estudio: Diagnostic_studies / Evaluation_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 2005 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acalasia del Esófago / Esfínter Esofágico Inferior Tipo de estudio: Diagnostic_studies / Evaluation_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 2005 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido