L-ascorbic acid 2-phosphate enhances the production of type I and type III collagen peptides in cultured rabbit keratocytes.
Ophthalmic Res
; 24(2): 68-72, 1992.
Article
en En
| MEDLINE
| ID: mdl-1608599
We studied the effect of L-ascorbic acid 2-phosphate (P-Asc), a long-acting phosphate derivative of L-ascorbic acid, on the production and secretion of type I and type III collagen peptides in cultured rabbit keratocytes using immunohistochemistry and enzyme immunoassay. P-Asc enhanced production and secretion of these collagen peptides. Our observations support a therapeutic role for P-Asc in the repair of corneal stromal damage such as caused by corneal chemical burn.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido Ascórbico
/
Colágeno
/
Procolágeno
/
Córnea
Límite:
Animals
Idioma:
En
Revista:
Ophthalmic Res
Año:
1992
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Suiza