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Critical points in the immunodiagnosis of cystic echinococcosis in humans.
Siracusano, A; Buttari, B; Delunardo, F; Profumo, E; Margutti, P; Ortona, E; Riganò, R; Teggi, A.
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  • Siracusano A; Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Roma, Italy. siracusano@iss.it
Parassitologia ; 46(4): 401-3, 2004 Dec.
Article en En | MEDLINE | ID: mdl-16044700
This study discusses the immunodiagnosis of cystic echinococcosis (ce, caused by Echinococcus granulosus). The detection by immunoblotting of antibodies specific for the 8 kDa subunit of antigen B and in particular the IgG4 subclass expression, seems the most promising serodiagnostic tool. Despite the development of molecular methods, nowadays there is no standard, highly sensitive, and specific test available for antibody detection in CE. Furthermore, because serological tests can give only a limited support to clinical findings there is a clear need for new advances in immunodiagnosis of E. granulosus infection.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Equinococosis Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Parassitologia Año: 2004 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Equinococosis Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Parassitologia Año: 2004 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia