Development of activity standard for 90 Y microspheres.
Appl Radiat Isot
; 63(2): 193-9, 2005 Aug.
Article
en En
| MEDLINE
| ID: mdl-15963429
(90)Y microspheres are important therapeutic radiopharmaceuticals used in the treatment of liver cancer through a process known as selective internal radiation therapy. SIR-spheres is a radiopharmaceutical product that is comprised of (90)Y microspheres suspended in sterile, pyrogen-free water for injection into patients. It is necessary to establish for the SIR-spheres production the capability of accurately measuring the activity of this product to a traceable national measurement standard. An activity standard for SIR-spheres was developed from a standard for (90)Y solution, employing a highly quantifiable chemical digestion process. Calibration factors for the manufacturer's ionisation chambers were determined for 1 and 5 ml of the SIR-spheres product placed in Wheaton vials, for both 34% and 44% of (90)Y microsphere concentration.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Garantía de la Calidad de Atención de Salud
/
Radiometría
/
Radioisótopos de Itrio
/
Radiofármacos
Tipo de estudio:
Evaluation_studies
/
Guideline
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Appl Radiat Isot
Asunto de la revista:
MEDICINA NUCLEAR
/
SAUDE AMBIENTAL
Año:
2005
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Reino Unido