Persistence of allergy to anaesthetic drugs.
Anaesth Intensive Care
; 20(2): 143-6, 1992 May.
Article
en En
| MEDLINE
| ID: mdl-1595846
Intradermal testing and RIA testing for specific IgE antibodies to neuromuscular blocking drugs (NMBDs) were performed in patients referred to an Anaesthetic Allergy Clinic. Six patients were initially investigated four to 29 years after clinical anaphylaxis during anaesthesia and two of these patients and sixteen others were investigated by intradermal testing on two occasions at least four years apart. Seven patients had RIA tests for NMBD-specific IgE antibodies on two occasions at the time of skin testing. In all but two patients the evidence for drug-specific antibodies persisted 4-29 years after the reactions. In one patient all tests became negative and in another the skin test became negative but the positive RIA persisted. Evidence of antibodies to NMBDs persisted in 21 of 22 patients who had had anaphylactic reactions to these drugs during anaesthesia. In the absence of evidence of allergy diminishing with time in the majority of patients it would seem wise to avoid drugs responsible for reactions for the rest of the patient's life.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hipersensibilidad a las Drogas
/
Bloqueantes Neuromusculares
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Anaesth Intensive Care
Año:
1992
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Estados Unidos