[In vitro study of oral Candida albicans in virulence from HIV-positive individuals].
Zhonghua Kou Qiang Yi Xue Za Zhi
; 40(3): 211-4, 2005 May.
Article
en Zh
| MEDLINE
| ID: mdl-15938881
OBJECTIVE: To study the influence of Candida albicans on human immunodeficiency virus (HIV)-positive individuals susceptible to oral candidiasis. METHODS: In vitro secreted aspartyl proteinase activities, adhesion to healthy buccal epithelial cells of Candida albicans isolates from oral cavities of subjects with and without HIV infection were measured. RESULTS: The pathogenetic isolates of Candida albicans from HIV-positive patients were significantly lower than that from HIV-negative subjects (P < 0.01) in secreted aspartyl proteinase activities and adhesion to buccal epithelial cells. There was no difference in commensals between these two groups. In the HIV-positive group, no difference was found between the pathogenetics and the commensals. However, in the HIV-negative group, the virulence of the pathogen was significantly higher than the commensals (P < 0.01). CONCLUSIONS: These results indicate that oral candidiasis was not correlated with some predominant strains of Candida albicans with higher virulence in HIV-positive subjects.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Candida albicans
/
Candidiasis Bucal
/
Síndrome de Inmunodeficiencia Adquirida
/
Seropositividad para VIH
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Kou Qiang Yi Xue Za Zhi
Asunto de la revista:
ODONTOLOGIA
Año:
2005
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
China