Quality control system for mass screening in Japan.
Southeast Asian J Trop Med Public Health
; 34 Suppl 3: 30-5, 2003.
Article
en En
| MEDLINE
| ID: mdl-15906689
Japan was the first country to establish a nationwide quality control system. When the Japanese Federal Government initiated Nationwide Neonatal Screening in 1977, the system officially included a Quality Control (QC) System that should cover all screening laboratories in Japan. This QC system is quite different from that for usual clinical chemistry. The aim of the National QC System for Neonatal Screening is evaluation of the accuracy of the tests and evaluation of the ability to detect suspicious samples with very mild abnormalities. For accomplishing the aim, the QC center established an inter-laboratory QC survey Screening laboratories having weak points can be identified through the inter-laboratory QC survey, and the Center must find a way to improve the ability of these screening laboratories. This requires a nationwide consensus regarding the cut-off levels of tested materials. Based on the cooperation of the Societies For Mass-screening, of Inborn Errors of Metabolism and of Pediatric Endocrinology, we set low cutoff levels for each compound to minimize the number of false negative cases. The system also included the evaluation of the quality of essential screening reagents and the special filter paper for blood collection (in partnership with the production companies). For this purpose, we developed some new methods for evaluating the standard-compounds for the various screening tests exactly, except in the case of TSH screening.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Control de Calidad
/
Tamizaje Neonatal
/
Gestión de la Calidad Total
/
Laboratorios
/
Errores Innatos del Metabolismo
/
Programas Nacionales de Salud
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Humans
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
Southeast Asian J Trop Med Public Health
Año:
2003
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Tailandia