Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields.
Mutat Res
; 583(2): 184-8, 2005 Jun 06.
Article
en En
| MEDLINE
| ID: mdl-15899587
The issue of adverse health effects of extremely low-frequency electromagnetic fields (ELF-EMFs) is highly controversial. Contradictory results regarding the genotoxic potential of ELF-EMF have been reported in the literature. To test whether this controversy might reflect differences between the cellular targets examined we exposed cultured cells derived from different tissues to an intermittent ELF-EMF (50 Hz sinusoidal, 1 mT) for 1-24h. The alkaline and neutral comet assays were used to assess ELF-EMF-induced DNA strand breaks. We could identify three responder (human fibroblasts, human melanocytes, rat granulosa cells) and three non-responder cell types (human lymphocytes, human monocytes, human skeletal muscle cells), which points to the significance of the cell system used when investigating genotoxic effects of ELF-EMF.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Daño del ADN
/
Campos Electromagnéticos
/
Fibroblastos
/
Células de la Granulosa
/
Melanocitos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Mutat Res
Año:
2005
Tipo del documento:
Article
País de afiliación:
Austria
Pais de publicación:
Países Bajos