Peptoids as source of compounds eliciting antibacterial activity.
Comb Chem High Throughput Screen
; 8(3): 235-9, 2005 May.
Article
en En
| MEDLINE
| ID: mdl-15892625
N-Alkylglycine oligomers (peptoids) constitute a family of non-natural peptidomimetics attractive for the early drug discovery process because of their physicochemical features, easy of adaptation to combinatorial chemistry approaches and their proteolytic stability. Consequently, peptoid libraries have found application for discovering hits against a wide diversity of pharmaceutical targets, among which different examples of antibacterials are found. In the present work, research efforts addressed towards the identification of peptoids as antibacterial agents are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bacterias
/
Técnicas Químicas Combinatorias
/
Peptoides
/
Antibacterianos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Comb Chem High Throughput Screen
Asunto de la revista:
BIOLOGIA MOLECULAR
/
QUIMICA
Año:
2005
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Emiratos Árabes Unidos