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A cholesterol-enriched diet enhances egg production and egg viability without altering cholesterol Content of biological membranes in the copepod Acartia hudsonica.
Crockett, Elizabeth L; Hassett, R Patrick.
Afiliación
  • Crockett EL; Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA. crockett@ohiou.edu
Physiol Biochem Zool ; 78(3): 424-33, 2005.
Article en En | MEDLINE | ID: mdl-15887089
Copepods may lack the capacity for de novo synthesis of cholesterol, while at the same time their dietary levels of sterol vary. We tested the hypothesis that copepods maintain the cholesterol contents of their biological membranes despite varying dietary levels of cholesterol. Acartia hudsonica were acclimated for 5 d to phytoplankton alone or phytoplankton supplemented with cholesterol, at a level sufficient to induce a maximal response on egg production rates. Biological membranes were prepared from the copepods and cholesterol contents assayed. Egg production and hatch rates were measured (the former to confirm that supplemented cholesterol was being assimilated). Analyses of marker enzymes indicate that the majority of membrane-associated cholesterol in the copepod resides in the plasma membrane. In membranes fractions, cholesterol normalized to protein or activity of Na+/K+-ATPase is not significantly different for supplemented and unsupplemented groups (29 and 33 mu g cholesterol mg(-1) protein, respectively; 0.24 and 0.25 mg cholesterol U(-1) Na+/K+-ATPase, respectively). At the same time, acclimating animals to a diet enriched with cholesterol enhances egg production by up to 1.8-fold and egg viability by 1.5-fold. We conclude that a cholesterol-enriched diet stimulates both egg production and hatching rates without altering cholesterol contents of plasma membranes in the copepod A. hudsonica.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Óvulo / Colesterol en la Dieta / Membrana Celular / Supervivencia Celular / Colesterol / Copépodos Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Physiol Biochem Zool Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2005 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Óvulo / Colesterol en la Dieta / Membrana Celular / Supervivencia Celular / Colesterol / Copépodos Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Physiol Biochem Zool Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2005 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos