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How necessary is vagotomy after pancreaticoduodenectomy and total pancreatectomy.
Safioleas, Michael C; Moulakakis, Konstantinos G; Andromanakos, Nikolaos P; Lygidakis, Nikolaos J.
Afiliación
  • Safioleas MC; 2nd Propaedeutic Surgical Department of University of Athens, Laiko Hospital, Athens, Greece.
Hepatogastroenterology ; 52(61): 251-2, 2005.
Article en En | MEDLINE | ID: mdl-15783042
BACKGROUND/AIMS: Gastrectomy with gastrojejunostomy is a fundamental step used for the restoration of the alimentary tract after pancreaticoduodenectomy or total pancreatectomy. Anastomotic ulcers occurring after pancreaticoduodenectomy, is a well known problem. The aim of our study is to investigate the incidence of anastomotic ulcer after pancreaticoduodenectomy or total pancreatectomy and to elucidate whether vagotomy is necessary. METHODOLOGY: In this study we reviewed the medical records of 94 patients who underwent pancreaticoduodenectomy or total pancreatectomy without vagotomy and we report the results after systemic follow-up 3-14 years, emphasizing the cases in which anastomotic ulcer is jeopardized. RESULTS: A total of 78 Whipple procedures and 16 total pancreatectomies without vagotomy were performed. The overall incidence of anastomotic ulceration following pancreatectomy was 11.7%. In our series the symptoms and complications associated with anastomotic ulceration were pain in 6 patients, bleeding in 4 patients and free perforation in one patient. Six patients needed a reoperation, the 4 patients with bleeding that underwent truncal vagotomy, the patient with free perforation in which oversew and bilateral vagotomy was performed and a patient with refractory pain who underwent a bilateral vagotomy. Among the 11 patients with anastomotic ulcer, the overall postoperative mortality rate was 27.3%. CONCLUSIONS: It seems reasonable to perform bilateral truncal vagotomy only in patients with a history of peptic ulceration and for patients with favorable prognosis and potential for long survival.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatectomía / Úlcera Péptica / Pancreaticoduodenectomía Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Hepatogastroenterology Año: 2005 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Grecia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatectomía / Úlcera Péptica / Pancreaticoduodenectomía Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Hepatogastroenterology Año: 2005 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Grecia