Immunopathological studies on the encystation phase of experimental trichinosis after cortisone and cyclophosphamide treatment.

Azab, M E; Sanad, M M; Kamel, A M; Nasr, M E

Azab, M E; Sanad, M M; Kamel, A M; Nasr, M E.

Afiliación

Azab ME; Department of Parasitology, Faculties of Medicine, Ain Shams University, Egypt.

J Egypt Soc Parasitol ; 22(1): 177-88, 1992 Apr.

Article en En | MEDLINE | ID: mdl-1578166

RESUMEN

Efficacy of cortisone and cyclophosphamide on the muscle phase of Trichinella spiralis in albino rats, before and after complete encapsulation, was studied by haematoxylin and eosin staining for histopathological changes and by the indirect immunoperoxidase test for the extent of antigen deposition. Results showing beneficial effects of cortisone and hazardous action of cyclophosphamide are discussed in details. This study indicates that the use of cortisone in the treatment of trichinosis remains to be substantiated particularly when administered before complete encystation; the time at which the diagnosis is usually made.

Asunto(s)

Cortisona/uso terapéutico; Ciclofosfamida/uso terapéutico; Músculos/parasitología; Trichinella/efectos de los fármacos; Triquinelosis/tratamiento farmacológico; Animales; Cortisona/farmacología; Ciclofosfamida/farmacología; Ratas

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trichinella / Triquinelosis / Cortisona / Ciclofosfamida / Músculos Límite: Animals Idioma: En Revista: J Egypt Soc Parasitol Año: 1992 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Egipto

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