Transferrin: structure, function and potential therapeutic actions.

Gomme, Peter T; McCann, Karl B; Bertolini, Joseph

Gomme, Peter T; McCann, Karl B; Bertolini, Joseph.

Afiliación

Gomme PT; Research and Development, CSL Ltd., Bioplasma Division, 189-209 Camp Road, Broadmeadows, Victoria 3047, Australia. Peter.Gomme@csl.com.au

Drug Discov Today ; 10(4): 267-73, 2005 Feb 15.

Article en En | MEDLINE | ID: mdl-15708745

RESUMEN

There are many proteins that can multi-task. Transferrin, widely known as an iron-binding protein, is one such example of a multi-tasking protein. In this review, the multiple biological actions of transferrin, including its growth and cytoprotective activities, are discussed with the view of highlighting the potential therapeutic applications of this protein.

Asunto(s)

Transferrina/química; Transferrina/fisiología; Animales; Antibacterianos/farmacología; Antiinfecciosos/uso terapéutico; Transporte Biológico; Trasplante de Médula Ósea; Enfermedades Cardiovasculares/tratamiento farmacológico; Humanos; Hierro/metabolismo; Neoplasias/tratamiento farmacológico; Radioterapia; Receptores de Transferrina/fisiología; Transferrina/uso terapéutico

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transferrina Límite: Animals / Humans Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2005 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

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