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[Blood activation during long-term mechanical circulatory support]. / L'activation sanguine au cours de l'assistance circulatoire mécanique prolongée.
Kirsch, M; Vermes, E; Boval, B; Tual, L; Mekontso-Dessap, A; Drouet, L; Loisance, D.
Afiliación
  • Kirsch M; Service de chirurgie thoracique et cardiovasculaire, CNRS UPRESA 7054, hôpital Henri-Mondor, 51 avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France. matthias.kirsch@hmn.ap-hop-paris.fr
Pathol Biol (Paris) ; 53(2): 97-104, 2005 Mar.
Article en Fr | MEDLINE | ID: mdl-15708654
Mechanical circulatory support has become an approved treatment option for patients with cardiogenic shock or end-stage heart failure. However, recipients of heart assist devices are prone to high incidences of bleeding, thrombo-embolic and infectious complications. The occurrence of these complications is favoured by systemic alterations of coagulation and fibrinolysis, inflammation and immune responses. Several studies have evaluated these pathophysiological changes in patients undergoing long term circulatory support with pulsatile devices. However, the systemic consequences of the more recently introduced rotary blood pumps remain largely unknown. The present review focuses on the systemic consequences of long term circulatory support with pulsatile and non-pulsatile devices.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Circulación Asistida / Corazón Auxiliar Tipo de estudio: Etiology_studies Límite: Humans Idioma: Fr Revista: Pathol Biol (Paris) Año: 2005 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Francia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Circulación Asistida / Corazón Auxiliar Tipo de estudio: Etiology_studies Límite: Humans Idioma: Fr Revista: Pathol Biol (Paris) Año: 2005 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Francia