Clinical effects of long-term use of neutralized dialysate for continuous ambulatory peritoneal dialysis.
Nephron
; 60(3): 324-9, 1992.
Article
en En
| MEDLINE
| ID: mdl-1565185
The long-term effects of neutralized dialysate used in continuous ambulatory peritoneal dialysis (CAPD) were evaluated in 8 well-controlled patients. Twelve milliliters of 8.4% sodium bicarbonate was added to Dianeal PD-1 immediately before every administration. The final pH was 6.8 and the concentration of sodium bicarbonate was 6 mmol/l. The final sodium level was 138 mEq/l. This dialysate was used for 5 months. For 2 months before and 3 months after this period, Dianeal PD-2 was used as the dialysate for comparison. Blood bicarbonate levels significantly improved during the use of the neutralized dialysate. Blood sodium, chloride and magnesium levels and the effluent volume significantly increased. Sodium balance improved during the period when neutralized dialysate was used. Total leukocyte counts in the effluent decreased, and leukocyte viability increased. Abdominal distention, abdominal pain during instillation, nausea and headache improved. No side effects, including peritonitis, occurred during the trial of neutralized dialysate. The results suggest that this dialysate was less irritating to the peritoneal membrane than the control dialysate and that the therapeutic effects were satisfactory.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diálisis Peritoneal Ambulatoria Continua
/
Electrólitos
/
Enfermedades Renales
Tipo de estudio:
Etiology_studies
Límite:
Humans
/
Middle aged
Idioma:
En
Revista:
Nephron
Año:
1992
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Suiza