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Impact of restricting fluoroquinolone prescription on bacterial resistance in an intensive care unit.
Aubert, G; Carricajo, A; Vautrin, A-C; Guyomarc'h, S; Fonsale, N; Page, D; Brunel, P; Rusch, P; Zéni, F.
Afiliación
  • Aubert G; Bacteriology Department, Bellevue University Hospital, Saint-Etienne, France. gerald.aubert@chu-st-etienne.fr
J Hosp Infect ; 59(2): 83-9, 2005 Feb.
Article en En | MEDLINE | ID: mdl-15620440
The purpose of this study was to assess the effect of reducing prescription of fluoroquinolones in an intensive care unit (ICU) upon bacterial resistance, particularly as regards Pseudomonas aeruginosa. For six months between January 2001 and June 2001, administration of fluoroquinolones was kept to a minimum. A bacteriological screening of patients was performed to assess the incidence of fluoroquinolone-resistant bacteria. There was a 75.8% restriction in prescriptions of fluoroquinolones. There was no significant change in bacterial ecology between the periods preceding (12 months) and following (12 months) restriction. There was a significant recovery of sensitivity of P. aeruginosa to ciprofloxacin (P
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Bacterianas / Infección Hospitalaria / Fluoroquinolonas / Farmacorresistencia Bacteriana Tipo de estudio: Incidence_studies / Prognostic_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Hosp Infect Año: 2005 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Bacterianas / Infección Hospitalaria / Fluoroquinolonas / Farmacorresistencia Bacteriana Tipo de estudio: Incidence_studies / Prognostic_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Hosp Infect Año: 2005 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido